Chemoenzymatic Synthesis of Sialic Acid Derivatives Using Immobilized N‐Acetylneuraminate Lyase in a Continuous Flow Reactor

The synthesis of N‐acetylneuraminic acid (Neu5Ac) derivatives is drawing more and more attention in glycobiology research because of the important role of sialic acids in e. g. cancer, bacterial, and healthy cells. Chemical preparation of these carbohydrates typically relies on multistep synthetic p...

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Bibliografske podrobnosti
izdano v:Adv Synth Catal
Main Authors: Bloemendal, Victor R. L. J., Moons, Sam J., Heming, Jurriaan J. A., Chayoua, Mohamed, Niesink, Olaf, van Hest, Jan C. M., Boltje, Thomas J., Rutjes, Floris P. J. T.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774325/
https://ncbi.nlm.nih.gov/pubmed/31598119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201900146
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