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Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment‐Based Drug Discovery

In recent years the pharmaceutical industry has benefited from the advances made in fragment‐based drug discovery (FBDD) with more than 30 fragment‐derived drugs currently marketed or progressing through clinical trials. The success of fragment‐based drug discovery is entirely dependent upon the com...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: King, Thomas A., Stewart, Hannah L., Mortensen, Kim T., North, Andrew J. P., Sore, Hannah F., Spring, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774287/
https://ncbi.nlm.nih.gov/pubmed/31598091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201900847
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