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Effects of Halothane on GABA(A) Receptor Kinetics: Evidence for Slowed Agonist Unbinding
Many anesthetics, including the volatile agent halothane, prolong the decay of GABA(A) receptor-mediated IPSCs at central synapses. This effect is thought to be a major factor in the production of anesthesia. A variety of different kinetic mechanisms have been proposed for several intravenous agents...
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| Veröffentlicht in: | J Neurosci |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6774186/ https://ncbi.nlm.nih.gov/pubmed/10648694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-03-00899.2000 |
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