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AMPA Receptor Calcium Permeability, GluR2 Expression, and Selective Motoneuron Vulnerability

AMPA receptor-mediated excitotoxicity is proposed to play a major pathogenic role in the selective motoneuron death of amyotrophic lateral sclerosis. Motoneurons have been shown in various models to be more susceptible to AMPA receptor-mediated injury than other spinal neurons. It has been hypothesi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Vandenberghe, Wim, Robberecht, Wim, Brorson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774105/
https://ncbi.nlm.nih.gov/pubmed/10627588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-01-00123.2000
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