Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma

Background: Exosomes are cell-derived vesicles and bear a specific set of nucleic acids including DNA (exoDNA). Thus, this study is to explore whether exoDNA in malignant pleural effusions (MPEs) could be a novel DNA source for mutation detection of epidermal growth factor receptor (EGFR). Methods:...

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Pubblicato in:Front Oncol
Autori principali: Qu, Xueling, Li, Qiuwen, Yang, Jingwen, Zhao, Huixia, Wang, Feifei, Zhang, Fengyun, Zhang, Shufang, Zhang, He, Wang, Ruliang, Wang, Qian, Wang, Qi, Li, Guanghui, Peng, Xiumei, Zhou, Xuan, Hao, Yixin, Zhu, Jianhua, Xiao, Wenhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773809/
https://ncbi.nlm.nih.gov/pubmed/31608233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00931
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