Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization

Fertilization is essential for species survival. Although Izumo1 and Juno are critical for initial interaction between gametes, additional molecules necessary for sperm:egg fusion on both the sperm and the oocyte remain to be defined. Here, we show that phosphatidylserine (PtdSer) is exposed on the...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rival, Claudia M., Xu, Wenhao, Shankman, Laura S., Morioka, Sho, Arandjelovic, Sanja, Lee, Chang Sup, Wheeler, Karen M., Smith, Ryan P., Haney, Lisa B., Isakson, Brant E., Purcell, Scott, Lysiak, Jeffrey J., Ravichandran, Kodi S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773685/
https://ncbi.nlm.nih.gov/pubmed/31575859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12406-z
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