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Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization

Fertilization is essential for species survival. Although Izumo1 and Juno are critical for initial interaction between gametes, additional molecules necessary for sperm:egg fusion on both the sperm and the oocyte remain to be defined. Here, we show that phosphatidylserine (PtdSer) is exposed on the...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Rival, Claudia M., Xu, Wenhao, Shankman, Laura S., Morioka, Sho, Arandjelovic, Sanja, Lee, Chang Sup, Wheeler, Karen M., Smith, Ryan P., Haney, Lisa B., Isakson, Brant E., Purcell, Scott, Lysiak, Jeffrey J., Ravichandran, Kodi S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773685/
https://ncbi.nlm.nih.gov/pubmed/31575859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12406-z
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