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The translational machinery of human CD4(+) T cells is poised for activation and controls the switch from quiescence to metabolic remodelling
Naïve T cells respond to TcR activation by leaving quiescence, remodelling metabolism, initiating expansion and differentiating toward effector cells. The molecular mechanisms coordinating the transition from naive to effector is central to the functioning of the immune system, but still elusive. He...
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| Udgivet i: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773601/ https://ncbi.nlm.nih.gov/pubmed/30197303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.08.009 |
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