EZH2 upregulates the PI3K/AKT pathway through IGF1R and MYC in clinically aggressive chronic lymphocytic leukaemia

EZH2 is overexpressed in poor-prognostic chronic lymphocytic leukaemia (CLL) cases, acting as an oncogene; however, thus far, the EZH2 target genes in CLL have not been disclosed. In this study, using ChIP-sequencing, we identified EZH2 and H3K27me3 target genes in two prognostic subgroups of CLL wi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Epigenetics
Κύριοι συγγραφείς: Kosalai, Subazini Thankaswamy, Morsy, Mohammad Hamdy Abdelrazak, Papakonstantinou, Nikos, Mansouri, Larry, Stavroyianni, Niki, Kanduri, Chandrasekhar, Stamatopoulos, Kostas, Rosenquist, Richard, Kanduri, Meena
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Taylor & Francis 2019
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773411/
https://ncbi.nlm.nih.gov/pubmed/31216925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1633867
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια