Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer

Human exposure to trichloroethylene (TCE) is linked to kidney cancer, autoimmune diseases, and probably non-Hodgkin lymphoma. Additionally, TCE exposed mice and cell cultures show altered DNA methylation. To evaluate associations between TCE exposure and DNA methylation in humans, we conducted an ep...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Phillips, Rachael V., Rieswijk, Linda, Hubbard, Alan E., Vermeulen, Roel, Zhang, Jinming, Hu, Wei, Li, Laiyu, Bassig, Bryan A., Wong, Jason Y.Y., Reiss, Boris, Huang, Yongshun, Wen, Cuiju, Purdue, Mark, Tang, Xiaojiang, Zhang, Luoping, Smith, Martyn T., Rothman, Nathaniel, Lan, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773405/
https://ncbi.nlm.nih.gov/pubmed/31241004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1633866
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