Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer

Human exposure to trichloroethylene (TCE) is linked to kidney cancer, autoimmune diseases, and probably non-Hodgkin lymphoma. Additionally, TCE exposed mice and cell cultures show altered DNA methylation. To evaluate associations between TCE exposure and DNA methylation in humans, we conducted an ep...

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Dades bibliogràfiques
Publicat a:Epigenetics
Autors principals: Phillips, Rachael V., Rieswijk, Linda, Hubbard, Alan E., Vermeulen, Roel, Zhang, Jinming, Hu, Wei, Li, Laiyu, Bassig, Bryan A., Wong, Jason Y.Y., Reiss, Boris, Huang, Yongshun, Wen, Cuiju, Purdue, Mark, Tang, Xiaojiang, Zhang, Luoping, Smith, Martyn T., Rothman, Nathaniel, Lan, Qing
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773405/
https://ncbi.nlm.nih.gov/pubmed/31241004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1633866
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