Glial Cell Line-Derived Neurotrophic Factor Is Essential for Postnatal Survival of Midbrain Dopamine Neurons

Glial cell line-derived neurotrophic factor (GDNF) is one of the most potent trophic factors that have been identified for midbrain dopamine (DA) neurons. Null mutations for trophic factor genes have been used frequently for studies of the role of these important proteins in brain development. One p...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Granholm, Ann-Charlotte, Reyland, Mary, Albeck, David, Sanders, Linda, Gerhardt, Greg, Hoernig, George, Shen, Liya, Westphal, Heiner, Hoffer, Barry
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773139/
https://ncbi.nlm.nih.gov/pubmed/10777782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03182.2000
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