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Reduction in the Density and Expression, But Not G-Protein Coupling, of Serotonin Receptors (5-HT(1A)) in 5-HT Transporter Knock-Out Mice: Gender and Brain Region Differences

The aim of the present study was to investigate the mechanisms underlying the desensitization of 5-HT(1A) receptors in the dorsal raphe and hypothalamus of serotonin (5-HT) transporter knock-out mice (5-HTT −/−). The density of 5-HT(1A) receptors in the dorsal raphe was reduced in both male and fema...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Li, Qian, Wichems, Christine, Heils, Armin, Lesch, Klaus-Peter, Murphy, Dennis L.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772750/
https://ncbi.nlm.nih.gov/pubmed/11050108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-21-07888.2000
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