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Tumor Necrosis Factor α Induces a Metalloprotease-Disintegrin, ADAM8 (CD 156): Implications for Neuron–Glia Interactions during Neurodegeneration
ADAM proteases, defined by extracellular disintegrin and metalloprotease domains, are involved in protein processing and cell–cell interactions. Using wobbler (WR) mutant mice, we investigated the role of ADAMs in neurodegeneration and reactive glia activation in the CNS. We found that ADAM8 (CD 156...
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| 發表在: | J Neurosci |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772711/ https://ncbi.nlm.nih.gov/pubmed/11050116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-21-07964.2000 |
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