Tumor Necrosis Factor α Induces a Metalloprotease-Disintegrin, ADAM8 (CD 156): Implications for Neuron–Glia Interactions during Neurodegeneration

ADAM proteases, defined by extracellular disintegrin and metalloprotease domains, are involved in protein processing and cell–cell interactions. Using wobbler (WR) mutant mice, we investigated the role of ADAMs in neurodegeneration and reactive glia activation in the CNS. We found that ADAM8 (CD 156...

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Publicado en:J Neurosci
Autores principales: Schlomann, Uwe, Rathke-Hartlieb, Silvia, Yamamoto, Shunsuke, Jockusch, Harald, Bartsch, Jörg W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2000
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ARTICLE
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772711/
https://ncbi.nlm.nih.gov/pubmed/11050116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-21-07964.2000
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