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Uncoupling of Myelin Assembly and Schwann Cell Differentiation by Transgenic Overexpression of Peripheral Myelin Protein 22

We have generated previously transgenic rats that overexpress peripheral myelin protein 22 (PMP22) in Schwann cells. In the nerves of these animals, Schwann cells have segregated with axons to the normal 1:1 ratio but remain arrested at the promyelinating stage, apparently unable to elaborate myelin...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Niemann, Stephan, Sereda, Michael W., Suter, Ueli, Griffiths, Ian R., Nave, Klaus-Armin
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772658/
https://ncbi.nlm.nih.gov/pubmed/10818147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-11-04120.2000
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