Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

Schwann cell development and peripheral nerve myelination require the serial expression of transcriptional activators, such as Sox10, Oct6/Scip/Pou3f1 and Egr2/Krox20. Here we show that also transcriptional repression, mediated by the zinc-finger protein Zeb2, is essential for differentiation and my...

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Foilsithe in:Nat Neurosci
Main Authors: Quintes, Susanne, Brinkmann, Bastian G, Ebert, Madlen, Fröb, Franziska, Kungl, Theresa, Arlt, Friederike A, Tarabykin, Victor, Huylebroeck, Danny, Meijer, Dies, Suter, Ueli, Wegner, Michael, Sereda, Michael W, Nave, Klaus-Armin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964942/
https://ncbi.nlm.nih.gov/pubmed/27294512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4321
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