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Reduction of Neuromuscular Activity Is Required for the Rescue of Motoneurons from Naturally Occurring Cell Death by Nicotinic-Blocking Agents

Spinal motoneurons (MNs) in the chick embryo undergo programmed cell death coincident with the establishment of nerve–muscle connections and the onset of synaptic transmission at the neuromuscular junction. Chronic treatment of embryos during this period with nicotinic acetylcholine receptor (nAChR)...

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Pubblicato in:J Neurosci
Autori principali: Oppenheim, Ronald W., Prevette, David, D'Costa, Anselem, Wang, Siwei, Houenou, Lucien J., McIntosh, J. Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772570/
https://ncbi.nlm.nih.gov/pubmed/10934261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-16-06117.2000
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