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Expression of Bcl-2 Protects against Photoreceptor Degeneration in retinal degeneration slow (rds) Mice

The retinal degeneration slow or rdsgene encodes rds/peripherin, an integral membrane glycoprotein in the outer segments of rod and cone photoreceptors. Mice homozygous for a null mutation in rds fail to develop outer segments and undergo subsequent degeneration of photoreceptors by the apoptotic pa...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nir, Izhak, Kedzierski, Wojciech, Chen, Jeannie, Travis, Gabriel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772515/
https://ncbi.nlm.nih.gov/pubmed/10704489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-06-02150.2000
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