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Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa

Retinitis pigmentosa (RP) is a group of inherited blinding diseases caused by mutations in multiple genes including RDS. RDS encodes rds/peripherin (rds), a 36-kDa glycoprotein in the rims of rod and cone outer-segment (OS) discs. Rom1 is related to rds with similar membrane topology and the identic...

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Bibliographische Detailangaben
Hauptverfasser: Kedzierski, Wojciech, Nusinowitz, Steven, Birch, David, Clarke, Geoff, McInnes, Roderick R., Bok, Dean, Travis, Gabriel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC35408/
https://ncbi.nlm.nih.gov/pubmed/11427722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141124198
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