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Axonal Regulation of Schwann Cell Proliferation and Survival and the Initial Events of Myelination Requires PI 3-Kinase Activity

In this report, we have investigated the signaling pathways that are activated by, and mediate the effects of, the neuregulins and axonal contact in Schwann cells. Phosphatidylinositol 3-kinase (PI 3-kinase) and mitogen-activated protein kinase kinase (MAPK kinase) are strongly activated in Schwann...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Maurel, Patrice, Salzer, James L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772460/
https://ncbi.nlm.nih.gov/pubmed/10844033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-12-04635.2000
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