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Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro

Axo-glial interactions are critical for myelination and the domain organization of myelinated fibers. Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode. Usin...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Chen, Ming-Shuo, Kim, Hyosung, Jagot-Lacoussiere, Léonard, Maurel, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073025/
https://ncbi.nlm.nih.gov/pubmed/27658374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23072
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