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Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro

Axo-glial interactions are critical for myelination and the domain organization of myelinated fibers. Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode. Usin...

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Bibliografiske detaljer
Udgivet i:Glia
Main Authors: Chen, Ming-Shuo, Kim, Hyosung, Jagot-Lacoussiere, Léonard, Maurel, Patrice
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073025/
https://ncbi.nlm.nih.gov/pubmed/27658374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23072
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