Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists

Alzheimer's disease (AD) is characterized by the extracellular deposition of β-amyloid fibrils within the brain and the subsequent association and phenotypic activation of microglial cells associated with the amyloid plaque. The activated microglia mount a complex local proinflammatory response...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Combs, Colin K., Johnson, Derrick E., Karlo, J. Colleen, Cannady, Steven B., Landreth, Gary E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772401/
https://ncbi.nlm.nih.gov/pubmed/10632585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-02-00558.2000
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