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Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion

Phage display is a powerful approach for evolving proteins and peptides with new functions, but the properties of the molecules that can be evolved are limited by the chemical diversity encoded. Herein, we report a system for incorporating non‐canonical amino acids (ncAAs) into proteins displayed on...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Oller‐Salvia, Benjamí, Chin, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771915/
https://ncbi.nlm.nih.gov/pubmed/31157495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902658
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