Lataa...

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

Antibody-drug conjugates (ADCs) used nowadays in clinical practice are mixtures of antibody molecules linked to a varying number of toxins at different positions. Preclinical studies have shown that the therapeutic index of these traditional ADCs can be improved by the site-specific linkage of toxin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Vis Exp
Päätekijä: Oller-Salvia, Benjamí
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MyJove Corporation 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235180/
https://ncbi.nlm.nih.gov/pubmed/30272643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58066
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!