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Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy

As one of the most prevalent post‐translational modifications in eukaryotic cells, ubiquitylation plays vital roles in many cellular processes, such as protein degradation, DNA metabolism, and cell differentiation. Substrate proteins can be tagged by distinct types of polymeric ubiquitin (Ub) chains...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chembiochem
Hauptverfasser: Zhao, Xiaohui, Mißun, Maite, Schneider, Tobias, Müller, Franziska, Lutz, Joachim, Scheffner, Martin, Marx, Andreas, Kovermann, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771822/
https://ncbi.nlm.nih.gov/pubmed/30920720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900146
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