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Renoprotective effect of irbesartan in a rat model of gentamicin-induced nephrotoxicity: Role of oxidative stress

BACKGROUND: The renin–angiotensin system (RAS) is essential in renal physiology; however, disturbance of the RAS is one of the chief pathways involved in renal injury. Dysregulation of RAS may result in both glomerular and tubulointerstitial injuries through direct effects of angiotensin II (Ang II)...

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Опубликовано в: :J Lab Physicians
Главные авторы: Al-Kuraishy, Hayder M., Al-Gareeb, Ali I., Al-Naimi, Marwa S.
Формат: Artigo
Язык:Inglês
Опубликовано: Wolters Kluwer - Medknow 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771317/
https://ncbi.nlm.nih.gov/pubmed/31579224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/JLP.JLP_136_18
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