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Sirtuin 7 promotes 45S pre-rRNA cleavage at site 2 and determines the processing pathway
In humans, ribosome biogenesis mainly occurs in nucleoli following two alternative pre-rRNA processing pathways differing in the order in which cleavages take place but not by the sites of cleavage. To uncover the role of the nucleolar NAD(+)-dependent deacetylase sirtuin 7 in the synthesis of ribos...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6771141/ https://ncbi.nlm.nih.gov/pubmed/31331964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.228601 |
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