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An RNA Conformational Switch Regulates Pre-18S rRNA Cleavage
To produce mature ribosomal RNAs (rRNAs), polycistronic rRNA transcripts are cleaved in an ordered series of events. We have uncovered the molecular basis for the ordering of two essential cleavage steps at the 3′-end of 18S rRNA. Using in vitro and in vivo structure probing, RNA binding and cleavag...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006654/ https://ncbi.nlm.nih.gov/pubmed/20934433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.09.064 |
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