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Challenges in the Design and Analysis of Non-Inferiority Trials: A Case Study

BACKGROUND: The literature on the design, conduct and analysis of non-inferiority (NI) trials is continuously evolving. Several design issues continue to be researched including the choice of active control, choice of NI margin and optimal analytic approaches. To date, there has been relatively litt...

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Detalhes bibliográficos
Publicado no:Clin Trials
Main Authors: Durkalski, Valerie, Silbergleit, Robert, Lowenstein, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771014/
https://ncbi.nlm.nih.gov/pubmed/21921062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774511418848
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