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The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy

Loss of cell cycle control is characteristic of tumorigenesis. The protein p21 is the founding member of cyclin-dependent kinase inhibitors and an important versatile cell cycle protein. p21 is transcriptionally controlled by p53 and p53-independent pathways. Its expression is increased in response...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Kreis, Nina-Naomi, Louwen, Frank, Yuan, Juping
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770903/
https://ncbi.nlm.nih.gov/pubmed/31438587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091220
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