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Heightened TLR7/9-Induced IL-10 and CXCL13 Production with Dysregulated NF-ҝB Activation in CD11c(hi)CD11b(+) Dendritic Cells in NZB/W F1 Mice

Systemic lupus erythematosus (SLE) is a chronic, multifactorial autoimmune disease that predominantly affects young females. Dysregulation of different immune cell populations leads to self-tolerance breakdown and subsequent multiple organ damage as the disease develops. Plasmacytoid dendritic cells...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yim, Lok Yan, Lau, Chak Sing, Chan, Vera Sau-Fong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770860/
https://ncbi.nlm.nih.gov/pubmed/31546763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184639
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