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BTLA Expression on Th1, Th2 and Th17 Effector T-Cells of Patients with Systemic Lupus Erythematosus Is Associated with Active Disease

An imbalanced T-cell homeostasis plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Co-stimulatory and co-inhibitory molecules regulate T-cell differentiation, survival, and cytokine production. B- and T-lymphocyte attenuator (BTLA) is a co-inhibitory molecule which n...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Oster, Christoph, Wilde, Benjamin, Specker, Christof, Sun, Ming, Kribben, Andreas, Witzke, Oliver, Dolff, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770819/
https://ncbi.nlm.nih.gov/pubmed/31514450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184505
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