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Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation

Papillary renal cell carcinoma (pRCC) is a malignant kidney cancer with a prevalence of 7–20% of all renal tumors. Proteome and metabolome profiles of 19 pRCC and patient-matched healthy kidney controls were used to elucidate the regulation of metabolic pathways and the underlying molecular mechanis...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ahmad, Ayham Al, Paffrath, Vanessa, Clima, Rosanna, Busch, Jonas Felix, Rabien, Anja, Kilic, Ergin, Villegas, Sonia, Timmermann, Bernd, Attimonelli, Marcella, Jung, Klaus, Meierhofer, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770591/
https://ncbi.nlm.nih.gov/pubmed/31484429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091298
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