Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity

The endocannabinoid system represents an integrated neuronal network involved in the control of several organisms’ functions, such as feeding behavior. A series of hybrids of 5-(4-chlorophenyl)-1-(2,4-dichloro-phenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (mimonabant), a well-known i...

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Foilsithe in:Biomolecules
Main Authors: Dimmito, Marilisa P., Stefanucci, Azzurra, Pieretti, Stefano, Minosi, Paola, Dvorácskó, Szabolcs, Tömböly, Csaba, Zengin, Gokhan, Mollica, Adriano
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770484/
https://ncbi.nlm.nih.gov/pubmed/31527522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090492
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