The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing

Oncogenic metadherin is a key contributor to tumourigenesis with metadherin expression and cytoplasmic localisation previously linked to poor survival. A number of reports have shown metadherin localises specifically to nuclear speckles known to be rich in RNA-binding proteins including the splicing...

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Udgivet i:Cancers (Basel)
Main Authors: Luxton, Hayley J., Simpson, Benjamin S., Mills, Ian G., Brindle, Nicola R., Ahmed, Zeba, Stavrinides, Vasilis, Heavey, Susan, Stamm, Stefan, Whitaker, Hayley C.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770463/
https://ncbi.nlm.nih.gov/pubmed/31450747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091233
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