Polycystin-1 Inhibits Cell Proliferation through Phosphatase PP2A/B56α

Autosomal dominant polycystic kidney disease (ADPKD) is associated with a number of cellular defects such as hyperproliferation, apoptosis, and dedifferentiation. Mutations in polycystin-1 (PC1) account for ∼85% of ADPKD. Here, we showed that wild-type (WT) or mutant PC1 composed of the last five tr...

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Publicat a:Biomed Res Int
Autors principals: Tang, Yan, Yang, JungWoo, Zheng, Wang, Tang, Jingfeng, Chen, Xing-Zhen, Yang, Jianzheng, Wang, Zuocheng
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770331/
https://ncbi.nlm.nih.gov/pubmed/31641668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2582401
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