Functional Dissection of pri-miR-290~295 in Dgcr8 Knockout Mouse Embryonic Stem Cells

The DiGeorge syndrome critical region gene 8 (Dgcr8) knockout strategy has been widely used to study the function of canonical microRNAs (miRNAs) in vitro and in vivo. However, primary miRNA (pri-miRNA) transcripts are accumulated in Dgcr8 knockout cells due to interrupted processing. Whether abnorm...

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Udgivet i:Int J Mol Sci
Main Authors: Shi, Ming, Hao, Jing, Wang, Xi-Wen, Liao, Le-Qi, Cao, Huiqing, Wang, Yangming
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770266/
https://ncbi.nlm.nih.gov/pubmed/31491855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184345
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