Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling

Ovarian cancer (OC) is the most lethal gynecologic cancer characterized by an elevated apoptosis resistance that, potentially, leads to chemo-resistance in the recurrent disease. Mitochondrial oxidative phosphorylation was found altered in OC, and mitochondria were proposed as a target for therapy....

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Signorile, Anna, De Rasmo, Domenico, Cormio, Antonella, Musicco, Clara, Rossi, Roberta, Fortarezza, Francesco, Palese, Luigi Leonardo, Loizzi, Vera, Resta, Leonardo, Scillitani, Giovanni, Cicinelli, Ettore, Simonetti, Francesca, Ferretta, Anna, Russo, Silvia, Tufaro, Antonio, Cormio, Gennaro
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770021/
https://ncbi.nlm.nih.gov/pubmed/31547300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091350
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