Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling

Ovarian cancer (OC) is the most lethal gynecologic cancer characterized by an elevated apoptosis resistance that, potentially, leads to chemo-resistance in the recurrent disease. Mitochondrial oxidative phosphorylation was found altered in OC, and mitochondria were proposed as a target for therapy....

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Pubblicato in:Cancers (Basel)
Autori principali: Signorile, Anna, De Rasmo, Domenico, Cormio, Antonella, Musicco, Clara, Rossi, Roberta, Fortarezza, Francesco, Palese, Luigi Leonardo, Loizzi, Vera, Resta, Leonardo, Scillitani, Giovanni, Cicinelli, Ettore, Simonetti, Francesca, Ferretta, Anna, Russo, Silvia, Tufaro, Antonio, Cormio, Gennaro
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770021/
https://ncbi.nlm.nih.gov/pubmed/31547300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091350
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