Immunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13–31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic Index

The anti-endotoxin activity of the cationic peptide LL-37 and its derivative IG-19 is attributed to electrostatic interaction of the peptides’ positive charge with negatively charged bacterial lipopolysaccharides (LPS), and in part to the alteration of intracellular mechanisms independent of peptide...

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Vydáno v:Biomolecules
Hlavní autoři: Hemshekhar, Mahadevappa, Faiyaz, Sana, Choi, Ka-Yee Grace, Krokhin, Oleg V., Mookherjee, Neeloffer
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769993/
https://ncbi.nlm.nih.gov/pubmed/31540479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090501
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