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Cellular Uptake and Clearance of Oxidatively-modified Apolipoprotein E3 by Cerebral Cortex Endothelial Cells

Apolipoprotein E3 (apoE3) plays a critical role in the metabolism of lipoproteins and lowers plasma lipid levels by serving as a ligand for the low-density lipoprotein receptor (LDLr) family of proteins and by promoting macrophage cholesterol efflux. The current study examines the effect of acrolein...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Cruz, Siobanth, Narayanaswami, Vasanthy
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769588/
https://ncbi.nlm.nih.gov/pubmed/31533203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184582
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