Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer’s disease

Systematic epistasis analyses in multifactorial disorders are an important step to better characterize complex genetic risk structures. We conducted a hypothesis-free sex-stratified genome-wide screening for epistasis contributing to Alzheimer’s disease (AD) susceptibility. We identified a statistic...

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Publicat a:Neurobiol Aging
Autors principals: Gusareva, Elena S., Twizere, Jean-Claude, Sleegers, Kristel, Dourlen, Pierre, Abisambra, Jose F., Meier, Shelby, Cloyd, Ryan, Weiss, Blaine, Dermaut, Bart, Bessonov, Kyrylo, van der Lee, Sven J., Carrasquillo, Minerva M., Katsumata, Yuriko, Cherkaoui, Majid, Asselbergh, Bob, Ikram, M. Arfan, Mayeux, Richard, Farrer, Lindsay A., Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Sims, Rebecca, Williams, Julie, Amouyel, Philippe, van Duijn, Cornelia M., Ertekin-Taner, Nilüfer, Van Broeckhoven, Christine, Dequiedt, Franck, Fardo, David W., Lambert, Jean-Charles, Van Steen, Kristel
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769421/
https://ncbi.nlm.nih.gov/pubmed/30201328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.08.001
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