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Metabolism‐induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells
Understanding how cellular activities impact genome stability is critical to multiple biological processes including tumorigenesis and reproductive biology. The fungal pathogen Candida albicans displays striking genome dynamics during its parasexual cycle as tetraploid cells, but not diploid cells,...
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發表在: | EMBO J |
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Main Authors: | , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
John Wiley and Sons Inc.
2019
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6769381/ https://ncbi.nlm.nih.gov/pubmed/31448850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101597 |
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