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Metabolism‐induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells

Understanding how cellular activities impact genome stability is critical to multiple biological processes including tumorigenesis and reproductive biology. The fungal pathogen Candida albicans displays striking genome dynamics during its parasexual cycle as tetraploid cells, but not diploid cells,...

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書目詳細資料
發表在:EMBO J
Main Authors: Thomson, Gregory J, Hernon, Claire, Austriaco, Nicanor, Shapiro, Rebecca S, Belenky, Peter, Bennett, Richard J
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769381/
https://ncbi.nlm.nih.gov/pubmed/31448850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101597
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