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IL-12 signaling drives the differentiation and function of a T(H)1-derived T(FH1)-like cell population

CD4(+) T follicular helper (T(FH)) cells provide help to B cells and promote antibody-mediated immune responses. Increasing evidence supports the existence of T(FH) populations that secrete cytokines typically associated with the effector functions of other CD4(+) T cell subsets. These include T hel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Powell, Michael D., Read, Kaitlin A., Sreekumar, Bharath K., Jones, Devin M., Oestreich, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769002/
https://ncbi.nlm.nih.gov/pubmed/31570752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50614-1
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