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An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis

During mammalian embryogenesis, extensive cellular remodeling is needed for tissue morphogenesis. As effectors of cytoskeletal dynamics, Rho GTPases and their regulators are likely involved, but their daunting complexity has hindered progress in dissecting their functions. We overcome this hurdle by...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Laurin, Melanie, Gomez, Nicholas C, Levorse, John, Sendoel, Ataman, Sribour, Megan, Fuchs, Elaine
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768663/
https://ncbi.nlm.nih.gov/pubmed/31556874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50226
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