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Distinct modes of cell competition shape mammalian tissue morphogenesis

Cell competition (CC)—the sensing and elimination of less fit “loser” cells by neighbouring “winner” cells—was first described in Drosophila. Although proposed as a selection mechanism to optimize tissue and organ development, its evolutionary generality remains unclear. Here, by employing live-imag...

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Bibliographic Details
Published in:Nature
Main Authors: Ellis, Stephanie J., Gomez, Nicholas C., Levorse, John, Mertz, Aaron F., Ge, Yejing, Fuchs, Elaine
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6638572/
https://ncbi.nlm.nih.gov/pubmed/31092920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1199-y
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