Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death

Autophagy plays multiple roles in host cells challenged with extracellular pathogens. Here, we aimed to explore whether autophagy inhibition could prevent bacterial infections. We first confirmed widely distinct patterns of autophagy responses in host cells infected with Staphylococcus aureus, as co...

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Vydáno v:J Biol Chem
Hlavní autoři: Radhi, Ohood A., Davidson, Scott, Scott, Fiona, Zeng, Run X., Jones, D. Heulyn, Tomkinson, Nicholas C. O., Yu, Jun, Chan, Edmond Y. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768650/
https://ncbi.nlm.nih.gov/pubmed/31387948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008923
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