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Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy

INTRODUCTION: Vacuolization is a frequently found morphological feature in acute myeloid leukemia (AML) blasts. Subcellular origin and biological function as well as prognostic impact are currently unknown. The aim of this study was to evaluate whether vacuolization correlates with clinically releva...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Ballo, Olivier, Stratmann, Jan, Serve, Hubert, Steffen, Björn, Finkelmeier, Fabian, Brandts, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768541/
https://ncbi.nlm.nih.gov/pubmed/31568521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223013
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