Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy

INTRODUCTION: Vacuolization is a frequently found morphological feature in acute myeloid leukemia (AML) blasts. Subcellular origin and biological function as well as prognostic impact are currently unknown. The aim of this study was to evaluate whether vacuolization correlates with clinically releva...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ballo, Olivier, Stratmann, Jan, Serve, Hubert, Steffen, Björn, Finkelmeier, Fabian, Brandts, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768541/
https://ncbi.nlm.nih.gov/pubmed/31568521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223013
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