Collagen VII Expression Is Required in Both Keratinocytes and Fibroblasts for Anchoring Fibril Formation in Bilayer Engineered Skin Substitutes

The blistering disease recessive dystrophic epidermolysis bullosa (RDEB) is caused by mutations in the gene encoding collagen VII (COL7), which forms anchoring fibrils that attach the epidermis to the dermis. Cutaneous gene therapy to restore COL7 expression in RDEB patient cells has been proposed,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Transplant
Prif Awduron: Supp, Dorothy M., Hahn, Jennifer M., Combs, Kelly A., McFarland, Kevin L., Schwentker, Ann, Boissy, Raymond E., Boyce, Steven T., Powell, Heather M., Lucky, Anne W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767893/
https://ncbi.nlm.nih.gov/pubmed/31271052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689719857657
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg